From Quora: My Answer to "Is it worth it to apply to an Ivy league University with a 33 ACT and 3.95 GPA? I'm a senior in a small town school in Oklahoma with no AP's of IB's available. I have taken all the honors offered to me though."

Probably - the worst thing they can say is “No.” I was accepted by a number of Ivy League colleges and universities, and my high school offered exactly two AP courses when I attended. If you have good extracurriculars, and have taken the most rigorous courses you can (i.e., the honors courses), you should apply. A 33 ACT is in the 99th percentile, according to the chart I just found by Googling “ACT percentile,” so you’re up to snuff.
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Being from a small town in Oklahoma does give you some geographic diversity points - universities and colleges do look for students from small towns in the country, sometimes calling them “rural reps,” etc. Hey, there’s nothing wrong with being a “rural rep”- some of the most accomplished students I knew at Williams College (not an Ivy, but as well-respected as most Ivies) were from small towns in the Midwest or the South. The best colleges and universities do want a representative sample of the whole U.S., as well as several international students, since diversity makes for a better learning environment. So yes, you should definitely apply, hopefully after figuring out what you want to do in college, and what colleges have the best faculty, staff, and possibly physical plant (hey, for high-level science, you may need equipment that’s only at certain colleges) for you. Showing the college you’ve “done your homework” by researching the faculty, etc. is always a plus when you apply. Good luck!